Featured: Sickle cell disease: wheeze or asthma?

Juan Carlos Ivancevich Monday, 18 April 2016 20:10

Child maltreatment and pediatric asthma: a review of the literature

Juan Carlos Ivancevich Tuesday, 12 April 2016 12:37

Hannah M. C. Schreier, Edith Chen and Gregory E. Miller

Abstract

Background

Child maltreatment is a common problem with known adverse consequences, yet its contributions to the development and course of pediatric asthma are only poorly understood.

Main

This review first describes possible pathways connecting child maltreatment to pediatric asthma, including aspects of the physical home environment, health behaviors and disease management, and psychological consequences of child maltreatment. We subsequently review existing studies, which generally report an association between maltreatment experiences and asthma outcomes in childhood. However, this literature is in its early stages; there are only a handful studies, most of them rely on self-reports of both child maltreatment and asthma history, and none have investigated the physiological underpinnings of this association. Taken together, however, the studies are suggestive of child maltreatment playing a role in pediatric asthma incidence and expression that should be explored further.

Conclusion

Existing data are sparse and do not allow for specific conclusions. However, the data are suggestive of child maltreatment influencing asthma risk and morbidity long before the adult years. Future research should focus on understanding how child maltreatment contributes to asthma disease risk and progression in this highly vulnerable population.

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CXC chemokine superfamily induced by Interferon-γ in asthma: a cross-sectional observational study

Juan Carlos Ivancevich Friday, 18 March 2016 12:49

 

 

 

 

Article alert

 

The following new article has just been published in Asthma Research and Practice

Research   

CXC chemokine superfamily induced by Interferon-γ in asthma: a cross-sectional observational study

Takaku Y, Soma T, Uchida Y, Kobayashi T, Nakagome K, Nagata M

Asthma Research and Practice 2016, 2 :6 (17 March 2016)

Abstract | Full Text | PDF

 

 

Treatment of asthma in young children: evidence-based recommendations

Juan Carlos Ivancevich Friday, 04 March 2016 15:57
 
 
 
Jose A. Castro-Rodriguez Email authorAdnan Custovic and Francine M. Ducharme

Abstract

In the present review, we focus on evidence-based data for the use of inhaled corticosteroids (ICS), leukotriene receptor antagonist (LTRA), long-acting beta2-agonits (LABA) and oral corticosteroids (OCS), with a special emphasis on well-performed randomized clinical trials (RCTs) and meta-analyses of such trials for the chronic management of asthma/wheeze in infants and preschoolers. Results: Seven meta-analyses and 14 RCTs were reviewed. Daily ICS should be the preferred drug for infants/preschoolers with recurrent wheezing, especially in asthmatics. For those with moderate or severe episodes of EVW, the use of high intermittent ICS doses significantly reduce the use of OCS. There is no evidence of effect of intermittent ICS at low-moderate dose in preschoolers with mild EVW episodes. In preschoolers with asthma, there were no significant differences between daily vs. intermittent ICS in terms of asthma exacerbations with insufficient power to conclude to equivalence; however, for other asthma control outcomes, daily ICS works significantly better than intermittent ICS for older children. Daily ICS is superior to daily or intermittent LRTA for reducing symptoms, preventing exacerbations, and improving lung function. No RCTs testing combination therapy with ICS and LABA (or LTRA) were published in infant/preschoolers. Parent-initiation of OCS at the first sign of symptoms is not effective in children with recurrent wheezing episode. In terms of ICS safety, growth suppression is dose and molecule-dependent but it’s effect is not cumulative beyond the first year of therapy and may be associated with some catch-up growth while on or off therapy. Linear growth must be monitored as individual susceptibility to ICS drugs may vary considerably.

Join WAO at Interasma for the COSA Symposium

Juan Carlos Ivancevich Wednesday, 02 March 2016 13:32

Join WAO at Interasma for the COSA Symposium: Approaches to Severe Asthma. WAO experts will present on severe asthma during Interasma’s World Congress on Asthma (WCA) in Madrid, Spain, on 14 March 2016 from 16:30 to 18:00.

Prof Lanny Rosenwasser will speak on “Cytokine Families and Receptors as Treatment Targets in Severe Asthma”. Prof Ignacio Ansotegui will speak on “Small Airways in Asthma”, and Prof Mario Sánchez-Borges will speak on “Acute Asthma Induced by Mite-Contaminated Foods.”

Upcoming Symposia

INTERASMA'S WORLD CONGRESS ON ASTHMA 2016 - MADRID, SPAIN

World Allergy Organization COSA Symposium: Approaches to Severe Asthma
Monday, 14 March 2016
16:30 to 18:00

Chairpersons:
G Walter Canonica, University of Genoa
Sergio Bonini, Second University of Naples

Cytokine Families and Receptors as Treatment Targets in Severe Asthma
Lanny Rosenwasser, Children’s Mercy Hospital

Small Airways in Asthma
Ignacio Ansotegui, Hospital Quirón Bizkaia

Acute Asthma Induced by Mite-Contamined Foods
Mario Sanchez-Borges, Centro Médico Docente – La Trinidad

http://www.wca-2016.com/

 

GINA will be present in the WCA 2016

Juan Carlos Ivancevich Thursday, 18 February 2016 19:30

XXIII World Congress of Asthma
March 12 – 15, 2016
Madrid Spain

 

Madrid is hosting the World Congress of Asthma, organized by the Global Asthma Association / Interasma from March 12 to 15, 2016, at Melia Castilla hotel.
 
The World Congress on Asthma (WCA 2016) will review the key findings from recent research on both adult and pediatric Asthma and how knowledge translation methods have evolved to better integrate research findings into care.
 
The origins and determinants of asthma, triggers and inducers, the new insight gained on the role of allergy, environmental and biodiversity changes, respiratory infections and various aspects of assessment of the disease are among the topics that will be covered through keynote lectures, debates, symposia and workshops by world experts, who will also be looking into the role of phenotyping/endotyping asthma, particularly when severe, and new therapeutic current and future advances.
 
GINA will be present in the WCA 2016 with an important and interesting Plenary Session on Sunday March 13, 03:00 pm as part of the excellent Scientific Program.


 
GINA GUIDELINES 2014-2015
 
Chairs:
Mark Levy, G. Walter Canonica
 
Mark Levy: “Lesson from a teenage asthma death – the case of Tamara Mills”
Louis Philippe-Boulet: “Adult asthma and ACOS”
Alvaró Cruz: “Exacerbations/Dissemination and implementation”
 
Take this excellent opportunity to hear and ask the GINA experts live and direct.
 
For more information on the Congress's full schedule can be found at www.wca-2016.com.
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World Congress of Asthma 2016. Madrid, March 12-15. General Information.

Juan Carlos Ivancevich Thursday, 11 February 2016 14:35

Congress Venue


Meliá Castilla

Calle del Capitán Haya, 43

Madrid 28020 

Spain

Climate and Dress Code


Madrid and its metropolitan area has a Mediterranean climate with continental influences, with mild cool winters and hot summers. The average temperature in March it varies from +8oC (46oF) to +20oC (60oF). The Spanish capital is in the center of the Iberian Peninsula, 622 meters above sea level. The dress code will be informal throughout the Congress.

Currency


The local currency is the Euro (EUR).

Exhibition


The WCA 2016 Congress in Madrid will include an exhibition that will be open from 12-15 March.
For more information regarding the exhibition and other sponsorship opportunities, please visit the Congress website or contact This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Language


The official language of the Congress is English.

 

Local Time


The time zone in Madrid is Central European Time (CEST / GMT +1) .

Visa


Participants are advised to make their own arrangements with respect to entering Spain.
If you need a letter of invitation, contact This email address is being protected from spambots. You need JavaScript enabled to view it.  after your registration fee is settled.
Please apply for a visa within a reasonable time prior to making your bookings.

Travel and Health Insurance


It is strongly recommended that all participants purchase adequate coverage for health, travel and private liability insurance before departing from their home countries. The Organizers will not accept responsibility for personal injury, loss or damage to private, personal property of participants, accompanying persons and exhibitors.

http://www.wca-2016.com/

The following new article has just been published in Asthma Research and Practice

Juan Carlos Ivancevich Tuesday, 09 February 2016 20:52

Research   

Once-daily fluticasone furoate/vilanterol versus twice daily combination therapies in asthma–mixed treatment comparisons of clinical efficacy

Svedsater H, Stynes G, Wex J, Frith L, Leather D, Castelnuovo E, Detry M, Berry S

Asthma Research and Practice 2016, 2 :4 (8 February 2016)

Abstract | Full Text | PDF

WCA 2016 - Venue and General Information

Juan Carlos Ivancevich Wednesday, 03 February 2016 14:54

Congress Venue


Meliá Castilla

Calle del Capitán Haya, 43

Madrid 28020 

Spain

 

Climate and Dress Code


Madrid and its metropolitan area has a Mediterranean climate with continental influences, with mild cool winters and hot summers. The average temperature in March it varies from +8oC (46oF) to +20oC (60oF). The Spanish capital is in the center of the Iberian Peninsula, 622 meters above sea level. The dress code will be informal throughout the Congress.

Currency


The local currency is the Euro (EUR).

Exhibition


The WCA 2016 Congress in Madrid will include an exhibition that will be open from 12-15 March.
For more information regarding the exhibition and other sponsorship opportunities, please visit the Congress website or contact This email address is being protected from spambots. You need JavaScript enabled to view it.

Language


The official language of the Congress is English.

Local Time


The time zone in Madrid is Central European Time (CEST / GMT +1) .

Visa


Participants are advised to make their own arrangements with respect to entering Spain.
If you need a letter of invitation, contact This email address is being protected from spambots. You need JavaScript enabled to view it.  after your registration fee is settled.
Please apply for a visa within a reasonable time prior to making your bookings.

Travel and Health Insurance


It is strongly recommended that all participants purchase adequate coverage for health, travel and private liability insurance before departing from their home countries. The Organizers will not accept responsibility for personal injury, loss or damage to private, personal property of participants, accompanying persons and exhibitors.

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Editor: Juan C. Ivancevich, MD

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