Mateja Marc Malovrh, PhD, MD, Mateja Marc Malovrh, Aleš Rozman, PhD, MD, Sabina Škrgat, PhD, MD, Mira Šilar, BSc, Julij Šelb, PhD, MD, Matjaž Fležar, PhD, MD, Peter Korošec, PhD
Abstract
Bronchial thermoplasty (BT) is a method of treating airways and randomized prospective trials have shown positive clinical effects of BT in patients with severe asthma.1 The mechanisms underlying BT airway treatment are not completely understood. Animal and human studies have shown that BT decreases airway smooth muscle mass and contraction.2 Because airway smooth muscle is a source of many proinflammatory factors and mediators, another result of BT could be the attenuation of airway inflammation.