| This new issue contains the following articles: Biomarkers Severe asthma in adult, inner-city predominantly African–American and latinx population: demographic, clinical and phenotypic characteristics Savneet Kaur, MBBS, David Rosenstreich, MD, Krystal L. Cleven, MD, Simon Spivack, MD, MPH, Joseph Grizzanti, DO, Marina Reznik, MD, MS & Sunit P. Jariwala, MD Pages: 2341-2351 | DOI: 10.1080/02770903.2021.2010748 Pharmacotherapy Asthma biologic trial eligibility and real-world outcomes in the United States Regina W. Lam, BA, Jonathan W. Inselman, MS, Molly M. Jeffery, PhD, Jacob T. Maddux, MD, Nilay D. Shah, PhD & Matthew A. Rank, MD Pages: 2352-2359 | DOI: 10.1080/02770903.2021.2010749 Montelukast and neuropsychiatric events – a sequence symmetry analysis Christopher W. Fox, PHARMD, Chelsea L. Khaw, PHARMD, BCPP, Alicia K. Gerke, MD & Brian C. Lund, PHARMD, MS Pages: 2360-2366 | DOI: 10.1080/02770903.2021.2018705 SMART therapy in adolescent and adults patients with moderate persistent asthma: a cost-utility analysis Jefferson Antonio Buendía, MD, PhD & Diana Guerrero Patiño, RN, MSc Pages: 2367-2374 | DOI: 10.1080/02770903.2021.2019266 Effectiveness of mepolizumab in patients with severe eosinophilic asthma: results from real-world clinical practice in Finland |  Ville Koistinen MD, PhD, Paula Kauppi MD, PhD, Juhana Idänpään-Heikkilä MD, PhD, Lauri Veijalainen MSc, Ilona Iso-Mustajärvi MSc, Tero Ylisaukko-oja PhD, Juha Mehtälä PhD, Arja Viinanen MD, PhD & Maritta Kilpeläinen MD, PhD Pages: 2375-2385 | DOI: 10.1080/02770903.2021.2020813 Quality improvement project to increase screening and referral for biologic therapy for patients with uncontrolled asthma Patricia Davis DNP, MS, RN, AGACNP-BC, Alison H. Edie, DNP, FNP-BC, FAANP, Sharron Rushton, DNP, MS, RN, CCM, CNE & Krystal Cleven, MD Pages: 2386-2394 | DOI: 10.1080/02770903.2021.2020814 Dupilumab as an adjunct treatment for a patient with steroid-dependent immunoglobulin G4-related disease complicated by asthma: a case report Toshihito Otani, MD, Hiroshi Iwamoto, MD, PhD, Yusuke Yoshida, MD, PhD, Kakuhiro Yamaguchi, MD, PhD, Shinjiro Sakamoto, MD, PhD, Yasushi Horimasu, MD, PhD, Takeshi Masuda, MD, PhD, Shintaro Miyamoto, MD, PhD, Taku Nakashima, MD, PhD, Kazunori Fujitaka, MD, PhD, Hironobu Hamada, MD, PhD, Shintaro Hirata, MD, PhD, Eiji Sugiyama, MD, PhD & Noboru Hattori, MD, PhD Pages: 2395-2401 | DOI: 10.1080/02770903.2021.2022158 Manifesto on inhaled triple therapy in asthma: an Interasma (Global Asthma Association – GAA) document Fulvio Braido MD, Angelica Tiotiu MD, PhD, Guillermo Guidos-Fogelbach MD, PhD(c), Ilaria Baiardini MD, Filippo Cosini MD, Jaime Correia de Sousa MD, PhD, Andras Bikov MD, PhD, Sylvia Novakova MD, PhD, Marina Labor MD, Igor Kaidashev MD, Denislava Nedeva MD, PhD, Krzysztof Kowal MD, PhD, Stefan Mihaicuta MD, PhD, Marilyn Urrutia Pereira MD, Dirceu Solé MD, Plamela Novakova MD, Herberto Chong-Neto MD, PhD, Laura Vrzy MD, Ignacio J. Ansotegui MD, PhD, Jonathan A. Bernstein MD, Louis-Philippe Boulet MD, PhD, Giorgio Walter Canonica MD, Lawrence Dubuske MD, PhD, Carlos Nunes MD, PhD, Juan Carlos Ivancevich MD, PhD, Pierachille Santus MD, PhD, Nelson Rosario MD, PhD, Alexander Emelyanov MD & Paschalis Steiropoulos MD, PhD Pages: 2402-2412 | DOI: 10.1080/02770903.2021.2022160 The use of puzzles in inhaler technique training Ahmet Kan MD & Velat Şen MD Pages: 2413-2420 | DOI: 10.1080/02770903.2022.2051542 Pediatric Asthma Ten year trends in hospital encounters for pediatric asthma: an Indiana experience Colin Rogerson, MD, Tian He, PhD, Courtney Rowan, MD, MS, Wanzhu Tu, PhD & Eneida Mendonca, MD, PhD Pages: 2421-2430 | DOI: 10.1080/02770903.2021.2010750 Telemedicine use for pediatric asthma care: a mixed methods study Sarah C. Haynes, PhD, MPH, Rory Kamerman-Kretzmer, MD, Shahabal S. Khan, MPH, Stephanie Crossen, MD, MPH, Monica K. Lieng, PhD, James P. Marcin, MD, MPH, Nicholas J. Kenyon, MD, MAS & Christopher H. Kim, MD, MPH Pages: 2431-2440 | DOI: 10.1080/02770903.2021.2019265 The impact of converting a power plant from coal to natural gas on pediatric acute asthma Robert Clemons MD, MPH, Maiying Kong PhD, Kahir Jawad MD, MPH, Yana Feygin MS & Kerry Caperell MD, MS, MBA Pages: 2441-2448 | DOI: 10.1080/02770903.2021.2022159 Asthma Control Determining the optimal threshold for medication adherence in adult asthma patients: an analysis of British Columbia administrative health database in Canada Michael Asamoah-Boaheng MPhil, PhD(c), Jamie Farrell BSc, MD, FRCPC, Kwadwo Osei Bonsu BPharm, PhD & William K. Midodzi, PhD Pages: 2449-2460 | DOI: 10.1080/02770903.2021.2014862 A multilevel perspective on goals, barriers, and facilitators of school-based asthma management Jennifer R. Mammen PhD, NP-BC, Colleen M. McGovern PhD, MPH, RN, Judith D. Schoonmaker MS, Ashley Philibert, Emma C. Schlegel RN, PhD, MPA & Kimberly Arcoleo PhD, MPH Pages: 2461-2474 | DOI: 10.1080/02770903.2021.2018704 The lived experience of adherence to asthma medication in young adults (18–34 years) Amal Al Wadhahi, B.Pharm, MRes, Loretta Garvey, PhD, Karen-Leigh Edward, PhD & Carolyn Beasley, PhD Pages: 2475-2490 | DOI: 10.1080/02770903.2021.2018706 Allergy to Der p 23 influences the cytokine profile in patients with allergic asthma – a preliminary study Andrzej Bożek MD, PhD, Jolanta Zalejska Fiolka MD, PhD, Zenon Czuba MD, PhD, Martyna Miodońska PhD & Renata Kozłowska MD, PhD Pages: 2491-2494 | DOI: 10.1080/02770903.2022.2083635 Asthma Outcomes Severe asthma exacerbation rates are increased among female, Black, Hispanic, and younger adult patients: results from the US CHRONICLE study | Njira Lugogo MD, Elizabeth Judson BSN, RN, Erin Haight Pharmd, Frank Trudo MD, MBA, Bradley E. Chipps MD, Jennifer Trevor MD & Christopher S. Ambrose MD, MBA Pages: 2495-2508 | DOI: 10.1080/02770903.2021.2018701 Clinical outcomes among hospitalized US adults with asthma or chronic obstructive pulmonary disease, with or without COVID-19 Cheryl R. Cornwell, MSPH, Joy Hsu, MD, MS, Lindsay K. Tompkins, PhD, MS, Audrey F. Pennington, PhD, MPH, W. Dana Flanders, MD, DSc & Kanta Sircar, PhD, MPH Pages: 2509-2519 | DOI: 10.1080/02770903.2021.2018703 Mechanisms Effects of high intensity interval training on cardiorespiratory fitness and salivary levels of IL-8, IL-1ra, and IP-10 in adults with asthma and non-asthma controls Carley D. O’Neill PhD, Ilana Patlan BHSC, Michael Jeffery PhD, Danielle Lewis BSc, Michael Jenkins MHSc, Holly Jones-Taggart PhD, Julia Green-Johnson PhD & Shilpa Dogra PhD Pages: 2520-2529 | DOI: 10.1080/02770903.2021.2018702 Interleukin (IL)-33 immunobiology in asthma and airway inflammatory diseases Rohit Gaurav MSc, PhD & Jill A. Poole MD Pages: 2530-2538 | DOI: 10.1080/02770903.2021.2020815 Environmental Determinants Family, neighborhood and psychosocial environmental factors and their associations with asthma in Australia: a systematic review and Meta-analysis K. M. Shahunja, MBBS, PG Dip, Peter D. Sly, MD, DSc, Tahmina Begum MBBS, MPH, Tuhin Biswas PhD & Abdullah Mamun PhD Pages: 2539-2552 | DOI: 10.1080/02770903.2021.2018707 |