Bianca Beghè, Antonio Spanevello, Leonardo M Fabbri
According to the latest version of the Global Initiative for Asthma strategy document,1 asthma is a heterogeneous disease with clinical manifestations sustained by different molecular mechanisms; in particular, these manifestations could be (but are not invariably) associated with chronic airway inflammation. Indeed, part of the heterogeneity of asthma might be due to different intensities or patterns of airway inflammation (eg, eosinophilic vs neutrophilic).
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