T helper 2 cells in asthma
Harker JA, Lloyd CM. J Exp Med. 2023 Jun 5;220(6):e20221094. doi: 10.1084/jem.20221094. Abstract: Allergic asthma is among the most common immune-mediated diseases across the world, and type 2 immune responses…
Childhood Asthma Not Associated With Total Consumption of Fruits and Vegetables
Colby Stong Total consumption of fruits and vegetables is not associated with the risk of asthma in children by age 5 years, according to a study in Pediatric Allergy and Immunology. Weak,…
Impact of a digital web-based asthma platform, a real-life study
Research – Open Access Emma M. Genberg, Hilkka T. Viitanen, Mika J. Mäkelä, Hannu J. Kautiainen & Paula M. Kauppi BMC Pulmonary Medicine volume 23, Article number: 165 (2023) Abstract Background Digital health technology (DHT) is a growing area in…
A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma
Alladina J, Smith NP, Kooistra T, Slowikowski K, Kernin IJ, Deguine J, Keen HL, Manakongtreecheep K, Tantivit J, Rahimi RA, Sheng SL, Nguyen ND, Haring AM, Giacona FL, Hariri LP,…
A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma
Alladina J, Smith NP, Kooistra T, et al. Sci Immunol. 2023 May 12;8(83):eabq6352. doi: 10.1126/sciimmunol.abq6352 Abstract Asthma is a chronic disease most commonly associated with allergy and type 2 inflammation.…
The effects of benralizumab on airway geometry and dynamics in severe eosinophilic asthma: a single-arm study design exploring a functional respiratory imaging approach
Eduardo Genofre, Donna Carstens, Wilfried DeBacker, Patrick Muchmore, Reynold A. Panettieri Jr, Kirsty Rhodes, Vivian H. Shih & Frank Trudo Respiratory Research volume 24, Article number: 121 (2023) Abstract Background Severe eosinophilic asthma (SEA) is characterised by elevated blood/sputum eosinophil counts and…
Number of Patient-Reported Asthma Triggers Predicts Uncontrolled Disease Burden
Colby Stong A better understanding of asthma triggers and their relationship to disease burden and health-related quality of life may help clinicians develop better asthma management plans with their patients.…
Development and Validation of a Respiratory-Responsive Vocal Biomarker–Based Tool for Generalizable Detection of Respiratory Impairment: Independent Case-Control Studies in Multiple Respiratory Conditions Including Asthma, Chronic Obstructive Pulmonary Disease, and COVID-19
Kaur S, Larsen E, Harper J, Purandare B, Uluer A, Hasdianda MA, Umale NA, Killeen J, Castillo E, Jariwala S. J Med Internet Res 2023;25:e44410 doi: 10.2196/44410 Abstract Background:Vocal biomarker–based machine learning approaches have shown promising results in the detection…
Pericytes: The lung-forgotten cell type
Front Physiol. 2023; 14: 1150028. Annelise T. Garrison, Rebecca E. Bignold, Xinhui Wu, and Jill R. Johnson Abstract Pericytes are a heterogeneous population of mesenchymal cells located on the abluminal surface of microvessels, where they…
Inhalation Devices in 7- to 15-Year-Old Children with Asthma – A Patient Preference Study
Authors Tietz F, Adams I, Lücke E, Schreiber J Patient Preference and Adherence Volume 17 DOI https://doi.org/10.2147/PPA.S381486 Background: Inhalation therapy is the cornerstone of treatment of bronchial asthma. A patient-specific selection of inhalation devices is necessary,…