Jackson, David J. et al. European Respiratory Journal 64.1 (2024): 2301521. Abstract Background Pivotal phase 3 trials and real-world studies have demonstrated benralizumab’s overall efficacy and safety in severe eosinophilic asthma (SEA). Additional large-cohort data are needed…
Mochizuki, H., Hirai, K., Furuya, H. et al. BMC Pulm Med 24, 394 (2024). https://doi.org/10.1186/s12890-024-03210-7 Abstract Background Lung sound analysis parameters have been reported to be useful biomarkers for evaluating airway condition. We…
Sugawara, H., Saito, A., Yokoyama, S. et al. Respir Res 25, 300 (2024). https://doi.org/10.1186/s12931-024-02921-z Abstract Background In recent years, the incorporation of LAMAs into asthma therapy has been expected to enhance symptom control.…
McDuffie, E.L., Panettieri, R.A. & Scott, C.P. Respir Res 25, 295 (2024). https://doi.org/10.1186/s12931-024-02920-0 Abstract Shortening of airway smooth muscle and bronchoconstriction are pathognomonic for asthma. Airway shortening occurs through calcium-dependent activation…
Huang, WC., Cheng, WC., Chen, CY. et al. BMC Pulm Med 24, 374 (2024). https://doi.org/10.1186/s12890-024-03190-8 Abstract Background Previous studies have reported reduced acute exacerbation rates and improved symptom control in asthma patients treated…
Afriyie-Mensah, J. S., Domoyeri, P., Antwi-Boasiako, C.et al. Annals of Medicine, 56(1). https://doi.org/10.1080/07853890.2024.2382377 Abstract Background Achieving disease control is the goal of asthma management. Serum or sputum eosinophil counts have…
Gu, W., Huang, C., Chen, G. et al. Respir Res 25, 290 (2024). https://doi.org/10.1186/s12931-024-02923-x Abstract Extracellular traps (ETs) are a specialized form of innate immune defense in which leukocytes release ETs composed of…
Castillo JR, Peters SP, Busse WW. J Allergy Clin Immunol Pract. 2017 Jul-Aug;5(4):918-927. doi: 10.1016/j.jaip.2017.05.001. Abstract Guideline-based management of asthma focuses on disease severity and choosing the appropriate medical therapy…
Wang, Y., Liu, L. BMC Immunol 25, 50 (2024). https://doi.org/10.1186/s12865-024-00644-w Abstract Asthma is a heterogeneous disease, and its development is the result of a combination of factors, including genetic factors,…
Xu, WJ., Shang, WY., Feng, JM. et al. Respir Res 25, 286 (2024). https://doi.org/10.1186/s12931-024-02911-1 Abstract Background The use of machine learning(ML) methods would improve the diagnosis of small airway dysfunction(SAD) in subjects with…