Raised sputum extracellular DNA confers lung function impairment and poor symptom control in an exacerbation-susceptible phenotype of neutrophilic asthma
Research – Open Access Mustafa Abdo, Mohib Uddin, Torsten Goldmann, Sebastian Marwitz, Thomas Bahmer, Olaf Holz, Anne-Marie Kirsten, Frederik Trinkmann, Erika von Mutius, Matthias Kopp, Gesine Hansen, Klaus F. Rabe, Henrik Watz, Frauke Pedersen on behalf of the ALLIANCE study group Respiratory Research volume 22, Article number: 167 (2021) Abstract…
Association between prevalence of obstructive lung disease and obesity: results from The Vermont Diabetes Information System
Research Open Access Maria E. Ramos-Nino, Charles D. MacLean & Benjamin Littenberg Asthma Research and Practice volume 7, Article number: 6 (2021) Abstract Background The association of obesity with the development of obstructive lung disease, namely asthma and/or…
RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma
Research – Open Access David Lamb, Dorothy De Sousa, Karsten Quast, Katrin Fundel-Clemens, Jonas S. Erjefält, Caroline Sandén, Hans Jürgen Hoffmann, Marc Kästle, Ramona Schmid, Kevin Menden & Denis Delic Respiratory Research volume 22, Article number: 158 (2021) Abstract Background RORγt is a transcription factor that…
Characteristics of inflammatory phenotypes among patients with asthma: relationships of blood count parameters with sputum cellular phenotypes
Research – Open Access Bingqing Shi, Wei Li, Yuqiu Hao, Hongna Dong, Wenjing Cao, Jie Guo & Peng Gao Allergy, Asthma & Clinical Immunology volume 17, Article number: 47 (2021) Abstract Background There is a need to identify the asthma inflammatory phenotypes…
2021 update of the Global Strategy for Asthma Management and Prevention
The 2021 update of the Global Strategy for Asthma Management and Prevention incorporates new scientific information about asthma based on a review of recent scientific literature by an international panel…
WORLD ASTHMA DAY 2021
Uncovering Asthma Misconceptions World Asthma Day (WAD) (May 5, 2021) is organized by the Global Initiative for Asthma, (GINA) (www.ginasthma.org), a World Health Organization collaborative organization founded in 1993. WAD…
European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years
Erol A. Gaillard, Claudia E. Kuehni, Steve Turner, Myrofora Goutaki, Karl A. Holden, Carmen C.M. de Jong, Christiane Lex, David K.H. Lo, Jane S. Lucas, Fabio Midulla, Rebeca Mozun, Giorgio Piacentini, David Rigau, Bart Rottier, Mike Thomas, Thomy Tonia, Jakob Usemann, Ozge Yilmaz, Angela Zacharasiewicz, Alexander Moeller European Respiratory Journal 2021; DOI: 10.1183/13993003.04173-2020 Abstract Diagnosing asthma in children represents an important clinical challenge. There is no single gold standard test to confirm…
EAACI Global Atlas of Asthma 2021 Update
Asthma is a major public health problem affecting more than 350 million patients around the world. Its prevalence and impact are particularly on the rise in urbanized regions and expanding…
Prevalence of overuse of short-acting beta-2 agonists (SABA) and associated factors among patients with asthma in Germany
Respiratory Research volume 22, Article number: 108 (2021) Research – Open Access Heinrich Worth, Carl-Peter Criée, Claus F. Vogelmeier, Peter Kardos, Eva-Maria Becker, Karel Kostev, Ingo Mokros & Andrea Schneider Background Overuse of short-acting beta-2 agonists (SABA), which do not treat the underlying…