The clinical impact of adherence to therapy in airways disease
Vincent Brennan, Christopher Mulvey, Richard W. Costello Breathe 2021 17: 210039; DOI: 10.1183/20734735.0039-2021 Abstract For a physician, the final step of a consultation consists of developing a treatment plan and prescription. For the patient, this is the start of a…
Neutralization of IL-33 modifies the type 2 and type 3 inflammatory signature of viral induced asthma exacerbation
Research – Open Access Kristi J. Warren, Jill A. Poole, Jenea M. Sweeter, Jane M. DeVasure, John D. Dickinson, R. Stokes Peebles Jr & Todd A. Wyatt Respiratory Research volume 22, Article number: 206 (2021) Abstract Background Respiratory viral infections are one…
Asthma and COVID-19: a dangerous liaison?
Review – Open Access Carlo Lombardi, Federica Gani, Alvise Berti, Pasquale Comberiati, Diego Peroni & Marcello Cottini Asthma Research and Practice volume 7, Article number: 9 (2021) Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by the new severe acute respiratory…
Risk factors for severe adult-onset asthma: a multi-factor approach
Research article – Open Access Sanna Toppila-Salmi, Riikka Lemmetyinen, Sebastien Chanoine, Jussi Karjalainen, Juha Pekkanen, Jean Bousquet & Valérie Siroux BMC Pulmonary Medicine volume 21, Article number: 214 (2021) Abstract Background The aim was to identify risk factors for severe adult-onset asthma.…
Pre-existing asthma as a comorbidity does not modify cytokine responses and severity of COVID-19
Research – Open Access Jian Luo, Yi-Ling Chen, Wentao Chen, David A. Duncan, Alexander Mentzer, Julian C. Knight, Graham Ogg, Paul Klenerman, Ian D. Pavord & Luzheng Xue Allergy, Asthma & Clinical Immunology volume 17, Article number: 67 (2021) Abstract Background A significant portion of…
Impact of baseline clinical asthma characteristics on the response to mepolizumab: a post hoc meta-analysis of two Phase III trials
Catherine Lemiere, Camille Taillé, Jason Kihyuk Lee, Steven G. Smith, Stephen Mallett, Frank C. Albers, Eric S. Bradford, Steven W. Yancey & Mark C. Liu Respiratory Research volume 22, Article number: 184 (2021) Abstract Background Severe asthma is associated with a broad range of…
SERPINB10 contributes to asthma by inhibiting the apoptosis of allergenic Th2 cells
Research – Open Access Yuqing Mo, Ling Ye, Hui Cai, Guiping Zhu, Jian Wang, Mengchan Zhu, Xixi Song, Chengyu Yang & Meiling Jin Abstract Background Serine peptidase inhibitor, clade B, member 10 (SERPINB10) contributes to allergic inflammation in asthma.…
Circulating miRNA expression in asthmatics is age-related and associated with clinical asthma parameters, respiratory function and systemic inflammation
Research – Open Access Aleksandra Wardzyńska, Małgorzata Pawełczyk, Joanna Rywaniak, Joanna Makowska, Joanna Jamroz-Brzeska & Marek L. Kowalski Respiratory Research volume 22, Article number: 177 (2021) Abstract Background The course of asthma may differ between elderly asthmatics (EA) and non-elderly asthmatics…
Digital asthma self-monitoring influences inhaled corticosteroid adherence, and decreased short-acting beta agonist use
Self-monitoring using a digital platform and remote clinician feedback helped patients maintain adherence to inhaled corticosteroids and decreased short-acting beta agonist use, researchers reported. “Poor adherence to inhaled corticosteroid-containing medications and overreliance…